SCHEMBL30891794

SCHEMBL30891794

COc1cc2c(-c3ccc(NC(=O)Cc4ccc(C(F)(F)F)nc4)cc3)ncnc2cc1OCC1CCN(C(C)C)CC1

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ PDGFRB P09619 9/20 0.45
▸ KDR P35968 5/20 0.45
▸ FLT3 P36888 4/20 0.45
▸ FLT4 P35916 3/20 0.45
▸ KIT P10721 4/20 0.44
▸ EGFR P00533 4/20 0.43
▸ CSF1R P07333 1/20 0.43
▸ CYP2C9 P11712 1/20 0.43
▸ ENPP1 P22413 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26135777 1.00 PDGFRB (0.45) PDGFRBKDRFLT3FLT4KIT
SCHEMBL30394725 0.93 KDR (0.52) KDRKITEGFR
SCHEMBL29238265 0.93 KDR (0.52) KDRKITEGFR
SCHEMBL29238239 0.91 PDGFRB (0.45) PDGFRBKDRFLT3FLT4KIT
SCHEMBL26534849 0.91 PDGFRB (0.45) PDGFRBKDRFLT3FLT4KIT
SCHEMBL30394353 0.91 PDGFRB (0.45) PDGFRBKDRFLT3FLT4KIT
SCHEMBL30393959 0.91 PDGFRB (0.45) PDGFRBKDRFLT3FLT4KIT
SCHEMBL26135248 0.91 KDR (0.46) PDGFRBKDRFLT3FLT4KIT
SCHEMBL30891776 0.90 PDGFRB (0.47) PDGFRBKDRFLT3FLT4KIT
SCHEMBL26535443 0.90 PDGFRB (0.47) PDGFRBKDRFLT3FLT4KIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260138959-A1 QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF VORONOI INC (KR) 2026-05-21 — — US claimed
EP-4424675-A1 QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF Voronoi Inc. (KR) 2024-09-04 — — EP claimed
CN-118201909-A Quinazoline derivative compound and use thereof 株式会社沃若诺伊 2024-06-14 — — CN claimed
EP-4424675-A1 QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF Voronoi Inc. (KR) 2024-09-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260138959-A1 QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF PDGFRA, KIT, PDGFRB PDGFRB 3/4885KDR 5/4885FLT3 26/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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