Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 19/20 | 0.58 |
| ▸ | TYRO3 | Q06418 | 14/20 | 0.51 |
| ▸ | FLT3 | P36888 | 13/20 | 0.51 |
| ▸ | GAS6 | Q14393 | 13/20 | 0.51 |
| ▸ | AXL | P30530 | 3/20 | 0.49 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29218464 | 1.00 | MERTK (0.58) | MERTKTYRO3FLT3GAS6AXL | |
| SCHEMBL29218466 | 1.00 | MERTK (0.58) | MERTKTYRO3FLT3GAS6AXL | |
| SCHEMBL29218449 | 0.96 | MERTK (0.53) | MERTKTYRO3FLT3GAS6AXL | |
| SCHEMBL29218442 | 0.96 | MERTK (0.53) | MERTKTYRO3FLT3GAS6AXL | |
| SCHEMBL30892304 | 0.96 | MERTK (0.53) | MERTKTYRO3FLT3GAS6AXL | |
| SCHEMBL30892293 | 0.96 | MERTK (0.53) | MERTKTYRO3FLT3GAS6AXL | |
| SCHEMBL29218441 | 0.96 | MERTK (0.53) | MERTKTYRO3FLT3GAS6AXL | |
| SCHEMBL30892311 | 0.95 | MERTK (0.63) | MERTKTYRO3FLT3GAS6AXL | |
| SCHEMBL29218512 | 0.95 | MERTK (0.63) | MERTKTYRO3FLT3GAS6AXL | |
| SCHEMBL29218510 | 0.95 | MERTK (0.63) | MERTKTYRO3FLT3GAS6AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117886798-A | Substituted benzimidazoles and use thereof | 河南中医药大学 | 2024-04-16 | — | — | CN | disclosed |