Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 6/20 | 0.49 |
| ▸ | JAK1 | P23458 | 4/20 | 0.49 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MERTK | Q12866 | 2/20 | 0.46 |
| ▸ | CDK1 | P06493 | 3/20 | 0.46 |
| ▸ | CDK4 | P11802 | 3/20 | 0.46 |
| ▸ | CCND1 | P24385 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29218489 | 1.00 | JAK3 (0.49) | JAK3JAK1NR2F2NPSR1KDM4E | |
| SCHEMBL29218488 | 1.00 | JAK3 (0.49) | JAK3JAK1NR2F2NPSR1KDM4E | |
| SCHEMBL29218501 | 0.92 | JAK3 (0.49) | JAK3JAK1NR2F2NPSR1KDM4E | |
| SCHEMBL30892302 | 0.92 | JAK3 (0.49) | JAK3JAK1NR2F2NPSR1KDM4E | |
| SCHEMBL29218503 | 0.92 | JAK3 (0.49) | JAK3JAK1NR2F2NPSR1KDM4E | |
| SCHEMBL30892296 | 0.91 | JAK3 (0.48) | JAK3JAK1NR2F2NPSR1KDM4E | |
| SCHEMBL29218449 | 0.91 | MERTK (0.53) | JAK3JAK1NR2F2NPSR1KDM4E | |
| SCHEMBL30892304 | 0.91 | MERTK (0.53) | JAK3JAK1NR2F2NPSR1KDM4E | |
| SCHEMBL30892293 | 0.91 | MERTK (0.53) | JAK3JAK1NR2F2NPSR1KDM4E | |
| SCHEMBL29218441 | 0.91 | MERTK (0.53) | JAK3JAK1NR2F2NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117886798-A | Substituted benzimidazoles and use thereof | 河南中医药大学 | 2024-04-16 | — | — | CN | disclosed |