Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 16/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 16/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCH | P24723 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30893291 | 1.00 | IRAK4 (0.44) | IRAK4DDB1CRBNPRKCGPRKCB | |
| SCHEMBL21069281 | 1.00 | IRAK4 (0.44) | IRAK4DDB1CRBNPRKCGPRKCB | |
| SCHEMBL21107388 | 0.96 | IRAK4 (0.43) | IRAK4DDB1CRBNPRMT5WDR77 | |
| SCHEMBL21106792 | 0.96 | IRAK4 (0.43) | IRAK4DDB1CRBNPRMT5WDR77 | |
| SCHEMBL29612710 | 0.96 | IRAK4 (0.43) | IRAK4DDB1CRBNPRMT5WDR77 | |
| SCHEMBL29612668 | 0.96 | IRAK4 (0.43) | IRAK4DDB1CRBNPRMT5WDR77 | |
| SCHEMBL24571632 | 0.94 | IRAK4 (0.49) | IRAK4DDB1CRBNCCR5PRMT5 | |
| SCHEMBL29641029 | 0.94 | IRAK4 (0.49) | IRAK4DDB1CRBNCCR5PRMT5 | |
| SCHEMBL30361084 | 0.93 | DDB1 (0.43) | IRAK4DDB1CRBN | |
| SCHEMBL30361088 | 0.93 | DDB1 (0.43) | IRAK4DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097948-A1 | DEGRADERS OF MDM2 AND USES THEREOF | ROIVANT DISCOVERY, INC. (US) | 2024-05-10 | — | — | WO | disclosed |