Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 6/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26813917 | 0.99 | KCNA3 (0.52) | KCNA3CTSKDRD2CCR5DRD3 | |
| SCHEMBL26814319 | 0.99 | KCNA3 (0.52) | KCNA3CTSKDRD2CCR5DRD3 | |
| SCHEMBL9092293 | 0.96 | KCNA3 (0.54) | KCNA3CTSKDRD2CCR5DRD3 | |
| SCHEMBL26813083 | 0.92 | KCNA3 (0.49) | KCNA3CTSKDRD2CCR5DRD3 | |
| SCHEMBL7222795 | 0.90 | KCNA3 (0.56) | KCNA3CTSKDRD2CCR5DRD3 | |
| SCHEMBL24690239 | 0.88 | KCNA3 (0.54) | KCNA3CTSKDRD2CCR5DRD3 | |
| SCHEMBL26813557 | 0.86 | KCNA3 (0.53) | KCNA3CTSKDRD2CCR5DRD3 | |
| SCHEMBL26814329 | 0.86 | KCNA3 (0.53) | KCNA3CTSKDRD2CCR5DRD3 | |
| SCHEMBL26814285 | 0.86 | KCNA3 (0.53) | KCNA3CTSKDRD2CCR5DRD3 | |
| SCHEMBL2828349 | 0.86 | KCNA3 (0.53) | KCNA3CTSKDRD2CCR5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097948-A1 | DEGRADERS OF MDM2 AND USES THEREOF | ROIVANT DISCOVERY, INC. (US) | 2024-05-10 | — | — | WO | disclosed |