Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 12/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29182308 | 1.00 | RET (0.49) | RETNR1H4POLBALDH1A1 | |
| SCHEMBL30893383 | 0.90 | RET (0.54) | RET | |
| SCHEMBL29182342 | 0.90 | RET (0.54) | RET | |
| SCHEMBL29182331 | 0.88 | RET (0.41) | RETNR1H4POLB | |
| SCHEMBL30893385 | 0.88 | RET (0.41) | RETNR1H4POLB | |
| SCHEMBL30893390 | 0.86 | RET (0.49) | RETNR1H4 | |
| SCHEMBL29182329 | 0.86 | RET (0.49) | RETNR1H4 | |
| SCHEMBL21801398 | 0.84 | RET (0.38) | RETNR1H4POLB | |
| SCHEMBL21178780 | 0.82 | RET (0.55) | RET | |
| SCHEMBL21801376 | 0.81 | RET (0.42) | RETNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813308-A | Nitrogen-containing condensed ring compound, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2024-04-02 | — | — | CN | disclosed |