Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29226875 | 0.89 | MAPT (0.60) | MAPTKDM4EALDH1A1HPGDTP53 | |
| SCHEMBL30248720 | 0.89 | MAPT (0.57) | MAPTKDM4EALDH1A1HPGDTP53 | |
| SCHEMBL30895157 | 0.84 | MAPT (0.58) | MAPTKDM4EALDH1A1HPGDTP53 | |
| SCHEMBL23769111 | 0.84 | MAPT (0.58) | MAPTKDM4EALDH1A1HPGDTP53 | |
| SCHEMBL29226906 | 0.83 | MAPT (0.59) | MAPTKDM4EALDH1A1HPGDTP53 | |
| SCHEMBL29226930 | 0.82 | MAPT (0.59) | MAPTKDM4EALDH1A1HPGDTP53 | |
| SCHEMBL23769038 | 0.81 | MAPT (0.74) | MAPTKDM4EALDH1A1HPGDTP53 | |
| SCHEMBL21905570 | 0.76 | MAPT (0.68) | MAPTKDM4EALDH1A1HPGDTP53 | |
| SCHEMBL23769051 | 0.75 | MAPT (0.64) | MAPTKDM4EALDH1A1HPGDTP53 | |
| SCHEMBL29978899 | 0.75 | MAPT (0.64) | MAPTKDM4EALDH1A1HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118019738-A | Small molecule urea derivatives as STING antagonists | 库拉德夫制药私人有限公司 | 2024-05-10 | — | — | CN | disclosed |