Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | LPL | P06858 | 8/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F11 | P03951 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30895247 | 0.90 | IDO1 (0.38) | IRAK4LPLLIPGIDO1TDO2 | |
| SCHEMBL31651744 | 0.81 | ADORA2A (0.46) | IRAK4LPLLIPGIDO1TDO2 | |
| SCHEMBL11165 | 0.81 | ADORA2A (0.46) | IRAK4LPLLIPGIDO1TDO2 | |
| SCHEMBL30895268 | 0.78 | IRAK4 (0.35) | IRAK4LPLLIPGFFAR1 | |
| SCHEMBL793617 | 0.75 | IRAK4 (0.40) | IRAK4LPLLIPGIDO1TDO2 | |
| SCHEMBL21025774 | 0.75 | IRAK4 (0.40) | IRAK4LPLLIPGIDO1TDO2 | |
| SCHEMBL17678142 | 0.73 | IRAK4 (0.38) | IRAK4LPLLIPGIDO1TDO2 | |
| SCHEMBL17678135 | 0.73 | IRAK4 (0.38) | IRAK4LPLLIPGIDO1TDO2 | |
| SCHEMBL21026014 | 0.73 | IRAK4 (0.38) | IRAK4LPLLIPGIDO1TDO2 | |
| SCHEMBL152838 | 0.72 | PRMT5 (0.45) | IRAK4IDO1TDO2PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4608507-A1 | COMPOUNDS AND COMPOSITIONS AS GPR52 MODULATORS | Neurocrine Biosciences, Inc. (US) | 2025-09-03 | — | — | EP | disclosed |
| WO-2024091538-A1 | COMPOUNDS AND COMPOSITIONS AS GPR52 MODULATORS | NEUROCRINE BIOSCIENCES, INC. (US) | 2024-05-02 | — | — | WO | disclosed |