SCHEMBL30895551

SCHEMBL30895551

CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)CCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.51
▸ TLR2 O60603 5/20 0.48
▸ TLR1 Q15399 1/20 0.48
▸ MDM2 Q00987 6/20 0.48
▸ KLK7 P49862 1/20 0.41
▸ KLK5 Q9Y337 1/20 0.41
▸ FOLH1 Q04609 2/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ ALDH1A1 P00352 1/20 0.41
▸ NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30895554 1.00 KMT2A (0.51) KMT2ATLR2TLR1MDM2KLK7
SCHEMBL30895422 0.98 KMT2A (0.49) KMT2ATLR2TLR1MDM2
SCHEMBL30895559 0.94 TLR2 (0.51) KMT2ATLR2TLR1MDM2KLK7
SCHEMBL30895488 0.94 TLR2 (0.52) KMT2ATLR2TLR1MDM2
SCHEMBL32670249 0.94 TLR2 (0.52) KMT2ATLR2TLR1MDM2
SCHEMBL34469052 0.94 TLR2 (0.52) KMT2ATLR2TLR1MDM2
SCHEMBL30895547 0.94 TLR2 (0.52) KMT2ATLR2TLR1MDM2
SCHEMBL20561672 0.94 TLR2 (0.52) KMT2ATLR2TLR1MDM2
SCHEMBL20561674 0.94 TLR2 (0.52) KMT2ATLR2TLR1MDM2
SCHEMBL29985390 0.94 TLR2 (0.52) KMT2ATLR2TLR1MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4608451-A1 CD70 ANTIBODY DRUG CONJUGATES AND METHODS OF USING THE SAME Genmab A/S (DK) 2025-09-03 — — EP disclosed
WO-2024092067-A1 CD70 ANTIBODY DRUG CONJUGATES AND METHODS OF USING THE SAME PROFOUNDBIO US CO. (US) 2024-05-02 — — WO disclosed
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