SCHEMBL30895581

SCHEMBL30895581

NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)NCC(NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN)C(=O)NCCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ TLR2 O60603 4/20 0.53
▸ KMT2A Q03164 1/20 0.44
▸ MDM2 Q00987 5/20 0.44
▸ TPSAB1 Q15661 1/20 0.42
▸ MDM4 O15151 1/20 0.40
▸ TP53 P04637 1/20 0.40
▸ CPB1 P15086 1/20 0.40
▸ CPB2 Q96IY4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30895410 0.95 TLR2 (0.52) TLR2KMT2AMDM2TPSAB1
SCHEMBL30895428 0.95 TLR2 (0.51) TLR2KMT2AMDM2TPSAB1
SCHEMBL30895556 0.92 TLR2 (0.55) TLR2KMT2AMDM2MDM4TP53
SCHEMBL32670225 0.92 TLR2 (0.55) TLR2KMT2AMDM2MDM4TP53
SCHEMBL34468954 0.92 TLR2 (0.55) TLR2KMT2AMDM2MDM4TP53
SCHEMBL32670236 0.89 TLR2 (0.47) TLR2KMT2AMDM2
SCHEMBL32670288 0.89 TLR2 (0.47) TLR2KMT2AMDM2
SCHEMBL30895420 0.89 KMT2A (0.52) TLR2KMT2AMDM2
SCHEMBL30895592 0.88 TLR2 (0.51) TLR2KMT2AMDM2
SCHEMBL30895604 0.88 TLR2 (0.50) TLR2KMT2AMDM2MDM4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4608451-A1 CD70 ANTIBODY DRUG CONJUGATES AND METHODS OF USING THE SAME Genmab A/S (DK) 2025-09-03 — — EP disclosed
WO-2024092067-A1 CD70 ANTIBODY DRUG CONJUGATES AND METHODS OF USING THE SAME PROFOUNDBIO US CO. (US) 2024-05-02 — — WO disclosed
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