SCHEMBL30895594

SCHEMBL30895594

NCCCC[C@H](NC(=O)CCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ TLR2 O60603 5/20 0.50
▸ KMT2A Q03164 2/20 0.50
▸ MDM2 Q00987 5/20 0.44
▸ CPB1 P15086 1/20 0.42
▸ CPB2 Q96IY4 1/20 0.42
▸ MDM4 O15151 1/20 0.41
▸ TP53 P04637 1/20 0.41
▸ FOLH1 Q04609 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30895420 0.93 KMT2A (0.52) TLR2KMT2AMDM2FOLH1
SCHEMBL26447022 0.92 TLR2 (0.53) TLR2KMT2AMDM2CPB1CPB2
SCHEMBL16329533 0.92 TLR2 (0.53) TLR2KMT2AMDM2CPB1CPB2
SCHEMBL29962125 0.91 KMT2A (0.55) TLR2KMT2AMDM2CPB1CPB2
SCHEMBL16329552 0.90 TLR2 (0.54) TLR2KMT2AMDM2CPB1CPB2
SCHEMBL19542037 0.90 TLR2 (0.49) TLR2KMT2ACPB1CPB2
SCHEMBL22514287 0.89 TLR2 (0.54) TLR2KMT2ACPB1CPB2
SCHEMBL19541911 0.89 TLR2 (0.56) TLR2KMT2ACPB1CPB2
SCHEMBL19542209 0.89 TLR2 (0.56) TLR2KMT2ACPB1CPB2
SCHEMBL24728974 0.89 KMT2A (0.56) TLR2KMT2AMDM2MDM4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4608451-A1 CD70 ANTIBODY DRUG CONJUGATES AND METHODS OF USING THE SAME Genmab A/S (DK) 2025-09-03 — — EP disclosed
WO-2024092067-A1 CD70 ANTIBODY DRUG CONJUGATES AND METHODS OF USING THE SAME PROFOUNDBIO US CO. (US) 2024-05-02 — — WO disclosed
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