Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27242483 | 1.00 | SCN10A (0.43) | SCN10AMAPTMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL30895687 | 0.88 | SCN10A (0.45) | SCN10AMAPTMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL30895680 | 0.82 | SCN10A (0.41) | SCN10AMAPTKMT2AMEN1 | |
| SCHEMBL27242543 | 0.82 | KMT2A (0.45) | SCN10AMAPTMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL27242534 | 0.81 | SCN10A (0.45) | SCN10AMAPTMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL30895722 | 0.79 | MAPT (0.46) | SCN10AMAPTMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL27242532 | 0.79 | MAPT (0.46) | SCN10AMAPTMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL27242638 | 0.78 | PDE8B (0.40) | KMT2A | |
| SCHEMBL24906276 | 0.78 | SCN10A (0.42) | SCN10AMAPTMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL27242469 | 0.77 | SCN10A (0.44) | SCN10AMAPTMAPK1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4385980-A1 | INDAZOLES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2024-06-19 | — | — | EP | disclosed |