Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | MERTK | Q12866 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RPS6KB2 | Q9UBS0 | 2/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.38 |
| ▸ | GSTP1 | P09211 | 3/20 | 0.37 |
| ▸ | GSTM2 | P28161 | 3/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16754633 | 1.00 | MAPT (0.61) | MAPTHTTMERTKLMNAFGFR4 | |
| SCHEMBL16238625 | 1.00 | MAPT (0.61) | MAPTHTTMERTKLMNAFGFR4 | |
| SCHEMBL16238623 | 1.00 | MAPT (0.61) | MAPTHTTMERTKLMNAFGFR4 | |
| SCHEMBL16775766 | 0.91 | MAPT (0.61) | MAPTHTTMERTKFGFR4ALDH1A1 | |
| SCHEMBL16775771 | 0.91 | MAPT (0.61) | MAPTHTTMERTKFGFR4ALDH1A1 | |
| SCHEMBL16237528 | 0.89 | MAPT (0.59) | MAPTHTTMERTKLMNAFGFR4 | |
| SCHEMBL16237530 | 0.89 | MAPT (0.59) | MAPTHTTMERTKLMNAFGFR4 | |
| SCHEMBL17767926 | 0.86 | MAPT (0.59) | MAPTHTTMERTKLMNAFGFR4 | |
| SCHEMBL16775781 | 0.86 | MAPT (0.61) | MAPTHTTMERTKFGFR4ALDH1A1 | |
| SCHEMBL16250005 | 0.84 | MAPT (0.62) | MAPTHTTMERTKLMNAFGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024078448-A1 | HPK1 KINASE INHIBITOR AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF | 珠海宇繁生物科技有限责任公司 | 2024-04-18 | — | — | WO | disclosed |