Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | IP6K1 | Q92551 | 3/20 | 0.41 |
| ▸ | RAF1 | P04049 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30898648 | 0.84 | MAPK14 (0.56) | MAPK14TDP2IP6K1RAF1PGR | |
| SCHEMBL30898618 | 0.83 | MAPK14 (0.57) | MAPK14TDP2IP6K1PGRMAP3K14 | |
| SCHEMBL30898677 | 0.83 | MAPK14 (0.69) | MAPK14TDP2RAF1PGRCYP1A2 | |
| SCHEMBL30898641 | 0.82 | MAPK14 (0.67) | MAPK14TDP2RAF1PGRCYP1A2 | |
| SCHEMBL30898662 | 0.81 | MAPK14 (0.55) | MAPK14TDP2IP6K1PGRMAP3K14 | |
| SCHEMBL30898723 | 0.81 | MAPK14 (0.55) | MAPK14TDP2IP6K1RAF1PGR | |
| SCHEMBL30898719 | 0.81 | MAPK14 (0.57) | MAPK14TDP2IP6K1PGR | |
| SCHEMBL30898627 | 0.80 | MAPK14 (0.54) | MAPK14TDP2IP6K1PGRMAP3K14 | |
| SCHEMBL30898632 | 0.74 | MAPK14 (0.60) | MAPK14TDP2RAF1PGR | |
| SCHEMBL12782697 | 0.69 | MAPK14 (1.00) | MAPK14RAF1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113330008-B | Preparation method of amide compound and application of amide compound in medicine field | 上海华汇拓医药科技有限公司 | 2024-05-07 | — | — | CN | disclosed |