SCHEMBL30898734

SCHEMBL30898734

COc1ccc(C(OC[C@@]23CN(S(C)(=O)=O)[C@@H]([C@H](n4cnc5c(NC(=O)c6ccccc6)ncnc54)O2)[C@@H]3OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TYMP P19971 1/20 0.33
PRMT6 Q96LA8 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA2B P29275 1/20 0.32
GAPDH P04406 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
ADORA1 P30542 1/20 0.31
PRKAG1 P54619 1/20 0.31
PRKAA1 Q13131 1/20 0.31
PRKAB1 Q9Y478 1/20 0.31
P2RY12 Q9H244 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23827254 1.00 TYMP (0.33) TYMPPRMT6ADORA2AADORA2BGAPDH
SCHEMBL23827276 0.92 TYMP (0.33) TYMPPRMT6ADORA2AADORA2BGAPDH
SCHEMBL23827278 0.92 TYMP (0.32) TYMPPRMT6ADORA2AADORA2BGAPDH
SCHEMBL30909499 0.92 TYMP (0.32) TYMPPRMT6ADORA2AADORA2BGAPDH
SCHEMBL23827286 0.92 TYMP (0.32) TYMPPRMT6ADORA2AADORA2BGAPDH
SCHEMBL31720750 0.92 TYMP (0.32) TYMPPRMT6ADORA2AADORA2BGAPDH
SCHEMBL31634928 0.92 TYMP (0.32) TYMPPRMT6ADORA2AADORA2BGAPDH
SCHEMBL20394008 0.91 TYMP (0.32) TYMPPRMT6ADORA2AADORA2BGAPDH
SCHEMBL20394038 0.90 TYMP (0.31) TYMPPRMT6
SCHEMBL5558224 0.89 TYMP (0.34) TYMPPRMT6ADORA2AADORA2BGAPDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119119156-A Bridged artificial nucleic acid ALNA 田边三菱制药株式会社 2024-12-13 CN claimed
CN-112996522-B Bridged artificial nucleic acid ALNA 田边三菱制药株式会社 2024-09-20 CN claimed
US-20250340584-A1 CROSSLINKED ARTIFICIAL NUCLEIC ACID ALNA MITSUBISHI TANABE PHARMA CORPORATION (JP) 2025-11-06 US disclosed
CN-119119156-A Bridged artificial nucleic acid ALNA 田边三菱制药株式会社 2024-12-13 CN disclosed
CN-112996522-B Bridged artificial nucleic acid ALNA 田边三菱制药株式会社 2024-09-20 CN disclosed
CN-117964674-A Bridged artificial nucleic acid ALNA 田边三菱制药株式会社 2024-05-03 CN disclosed
CN-117964673-A Bridged artificial nucleic acid ALNA 田边三菱制药株式会社 2024-05-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250340584-A1 CROSSLINKED ARTIFICIAL NUCLEIC ACID ALNA POLN, DDX21, MUS81 TYMP 1322/4885PRMT6 2183/4885ADORA2A 1638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.