SCHEMBL30899477

SCHEMBL30899477

Cc1ccccc1CC(=O)NC1CCC(=O)NC1=O

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 17/20 0.56
DDB1 Q16531 9/20 0.56
IKZF3 Q9UKT9 1/20 0.48
P2RX7 Q99572 1/20 0.46
GSPT1 P15170 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22158629 1.00 CRBN (0.56) CRBNDDB1IKZF3P2RX7GSPT1
SCHEMBL22564725 0.85 CRBN (0.65) CRBNDDB1IKZF3
SCHEMBL4401471 0.83 CRBN (0.51) CRBNDDB1
SCHEMBL22158581 0.82 CRBN (0.54) CRBNDDB1IKZF3P2RX7
SCHEMBL28419421 0.82 CRBN (0.54) CRBNDDB1IKZF3P2RX7
Antineoplaston A10 SCHEMBL20772654 0.81 CRBN (0.69) CRBNDDB1IKZF3
Antineoplaston A10 SCHEMBL19370609 0.81 CRBN (0.69) CRBNDDB1IKZF3
Antineoplaston A10 SCHEMBL2483037 0.81 CRBN (0.69) CRBNDDB1IKZF3
SCHEMBL24717776 0.79 CRBN (0.57) CRBNDDB1IKZF3GSPT1
SCHEMBL23267776 0.79 CRBN (0.72) CRBNDDB1IKZF3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118108706-A Glutarimide C4医药公司 2024-05-31 CN disclosed
CN-111278815-B Glutarimide C4医药公司 2024-03-08 CN disclosed