Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | BCL6B | Q8N143 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MELK | Q14680 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30899553 | 1.00 | BCL6 (0.50) | BCL6KDM4ESMN1; SMN2ALDH1A1CHRM4 | |
| SCHEMBL20267462 | 0.82 | BCL6 (0.54) | BCL6KDM4ESMN1; SMN2ALDH1A1CHRM4 | |
| SCHEMBL21774715 | 0.79 | BCL6 (0.49) | BCL6SMN1; SMN2ALDH1A1CHRM4BCL6B | |
| SCHEMBL23267671 | 0.76 | BCL6 (0.55) | BCL6KDM4ETP53MEN1KMT2A | |
| SCHEMBL20284512 | 0.75 | BCL6 (0.44) | BCL6SMN1; SMN2ALDH1A1CHRM4BCL6B | |
| SCHEMBL20284361 | 0.73 | BCL6 (0.73) | BCL6CHRM4BCL6BMELKNCOR2 | |
| SCHEMBL22528395 | 0.72 | BCL6 (0.52) | BCL6SMN1; SMN2ALDH1A1POLBTP53 | |
| SCHEMBL20267767 | 0.72 | BCL6 (0.54) | BCL6KDM4ESMN1; SMN2ALDH1A1CHRM4 | |
| SCHEMBL434941 | 0.72 | CYP19A1 (0.56) | KDM4EALDH1A1HSD17B10POLBMEN1 | |
| SCHEMBL21787618 | 0.72 | BCL6 (0.42) | BCL6KDM4ESMN1; SMN2ALDH1A1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118047758-A | Chimeric molecule targeting BCL6 protein degradation and application thereof | 西南交通大学 | 2024-05-17 | — | — | CN | disclosed |