Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22714362 | 1.00 | NPC1 (0.37) | NPC1POLBVCAM1THRBMEN1 | |
| SCHEMBL29438157 | 0.91 | MAPT (0.38) | NPC1VCAM1MEN1RAB9AKMT2A | |
| SCHEMBL21635547 | 0.91 | MAPT (0.38) | NPC1VCAM1MEN1RAB9AKMT2A | |
| SCHEMBL22714373 | 0.86 | NPSR1 (0.40) | NPC1POLBMEN1RAB9AKMT2A | |
| SCHEMBL30899559 | 0.86 | NPSR1 (0.40) | NPC1POLBMEN1RAB9AKMT2A | |
| SCHEMBL30899560 | 0.83 | F10 (0.40) | NPC1MEN1RAB9AKMT2AMAPK1 | |
| SCHEMBL22714488 | 0.83 | F10 (0.40) | NPC1MEN1RAB9AKMT2AMAPK1 | |
| SCHEMBL29055133 | 0.80 | MAPT (0.35) | NPC1POLBMEN1RAB9AKMT2A | |
| SCHEMBL22714402 | 0.79 | CA1 (0.33) | SMN1; SMN2 | |
| SCHEMBL30899556 | 0.79 | CA1 (0.33) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113874368-B | Herbicidal compounds | 先正达农作物保护股份公司 | 2024-03-08 | — | — | CN | disclosed |