⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24450597 | 1.00 | — | — | |
| SCHEMBL4610848 | 0.83 | TSHR (0.50) | — | |
| SCHEMBL7162514 | 0.82 | HTR2A (0.40) | — | |
| SCHEMBL600559 | 0.81 | MAPT (0.48) | — | |
| SCHEMBL10929741 | 0.80 | TSHR (0.68) | — | |
| SCHEMBL13890690 | 0.77 | TSHR (0.50) | — | |
| SCHEMBL15471196 | 0.75 | TSHR (0.42) | — | |
| SCHEMBL168774 | 0.75 | TSHR (0.69) | — | |
| SCHEMBL14113732 | 0.75 | TSHR (0.69) | — | |
| SCHEMBL12123463 | 0.74 | MAPT (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2204394-B1 | PROCESS FOR PRODUCTION OF POLYESTER-CONTAINING FLEXIBLE POLYURETHANE FOAM, AND CATALYST COMPOSITION FOR USE IN THE PROCESS | TOSOH CORP (JP) | 2017-07-12 | — | — | EP | disclosed |
| US-9139609-B2 | C-4″ position substituted macrolide derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |
| US-8980965-B2 | Method for producing polyester type flexible polyurethane foam, and catalyst composition to be used therefor | TOSOH CORPORATION (JP) | 2015-03-17 | — | — | US | disclosed |
| US-20140046043-A1 | C-4\" POSITION SUBSTITUTED MACROLIDE DERIVATIVE | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2014-02-13 | — | — | US | disclosed |
| CN-101835820-B | Process for production of polyester-containing flexible polyurethane foam, and catalyst composition for use in the process | TOSOH CORP | 2012-11-21 | — | — | CN | disclosed |
| US-20100256249-A1 | METHOD FOR PRODUCING POLYESTER TYPE FLEXIBLE POLYURETHANE FOAM, AND CATALYST COMPOSITION TO BE USED THEREFOR | TOSOH CORPORATION (JP) | 2010-10-07 | — | — | US | disclosed |
| CN-101835820-A | Process for production of polyester-containing flexible polyurethane foam, and catalyst composition for use in the process | TOSOH CORP | 2010-09-15 | — | — | CN | disclosed |
| EP-2204394-A1 | PROCESS FOR PRODUCTION OF POLYESTER-CONTAINING FLEXIBLE POLYURETHANE FOAM, AND CATALYST COMPOSITION FOR USE IN THE PROCESS | Tosoh Corporation (JP) | 2010-07-07 | — | — | EP | disclosed |
| EP-1074541-B1 | Method for manufacturing aminoalcohol | KURARAY CO LTD KURASHIKI PLANT (JP) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007025886-A1 | RIGID POLYURETHANE FOAM AND METHOD FOR THE PRODUCTION THEREOF | BASF SE (DE) | 2007-03-08 | — | — | WO | disclosed |
| US-6767929-B2 | CATALYSIS USING DIALKYLAMINOALKYL ALCOHOL | KAO CORPORATION (JP) | 2004-07-27 | — | — | US | disclosed |
| EP-1270630-A1 | PROCESS FOR PRODUCING POLYURETHANE | Kao Corporation (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-20030004220-A1 | Process for producing polyurethane | KAO CORPORATION (JP) | 2003-01-02 | — | — | US | disclosed |
| US-6331650-B1 | Method for manufacturing aminoalcohol | KURARAY CO., LTD. (JP) | 2001-12-18 | — | — | US | disclosed |
| EP-1074541-A1 | Method for manufacturing aminoalcohol | Kuraray Co., Ltd., Kurashiki Plant (JP) | 2001-02-07 | — | — | EP | disclosed |