Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30133858 | 0.90 | TSHR (0.40) | RAB9AHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16100241 | 0.81 | ELANE (0.38) | RAB9AHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20517501 | 0.81 | MAPT (0.38) | RAB9AHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL31622731 | 0.81 | ELANE (0.38) | RAB9AHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30133793 | 0.81 | GAA (0.42) | RAB9AHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16100242 | 0.81 | ELANE (0.38) | RAB9AHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30900043 | 0.80 | CYP1A2 (0.34) | HPGDCYP1A2TSHRALDH1A1KDM4E | |
| SCHEMBL30900034 | 0.80 | GAA (0.34) | RAB9AHPGDCYP1A2NPC1TSHR | |
| SCHEMBL30134356 | 0.77 | MAPT (0.39) | HPGDTSHRELANEALDH1A1SMN1; SMN2 | |
| SCHEMBL30133959 | 0.76 | ELANE (0.38) | RAB9AHPGDCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119119033-A | Pyrazolopyridone compounds | 百济神州有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-117836296-A | Pyrazolopyridone compounds | 百济神州有限公司 | 2024-04-05 | — | — | CN | disclosed |