Sugi Predict

Sugi Predict / Compounds / SCHEMBL30900795

SCHEMBL30900795

SCHEMBL30900795

CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(C)C)C(C)C)[C@@H](C)O)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ NPY2R P49146 8/20 0.57
▸ NPY4R P50391 8/20 0.57
▸ NPY5R Q15761 8/20 0.57
▸ NPY1R P25929 6/20 0.57
▸ RAMP3 O60896 9/20 0.54
▸ CALCR P30988 9/20 0.54
▸ EP300 Q09472 1/20 0.54
▸ HIF1A Q16665 1/20 0.54
▸ MAPK8 P45983 1/20 0.53
▸ MAPK9 P45984 1/20 0.53
▸ MAPK10 P53779 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Qatvgdvntdrpglldlk SCHEMBL30399126 0.96 NPY2R (0.60) NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL30900803 0.94 NPY2R (0.52) NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL30900792 0.93 NPY2R (0.53) NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL29424684 0.90 RAMP3 (0.56) NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL31211774 0.90 NPY2R (0.57) NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL30429234 0.89 EP300 (0.62) NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL30900802 0.89 NPY2R (0.56) NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL29403493 0.88 RAMP3 (0.57) NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL29742975 0.88 MAPK8 (0.56) NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL31031572 0.88 RAMP3 (0.59) NPY2RNPY4RNPY5RNPY1RRAMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4618957-A1 COMPOSITIONS COMPRISING OCTADECANEUROPEPTIDES (ODN) AND SYNTHETIC DERIVATIVES THEREOF AND METHODS OF USE FOR MODULATION OF FOOD INTAKE, OBESITY, BODY WEIGHT, NAUSEA, AND EMESIS The Trustees of The University of Pennsylvania (US) 2025-09-24 — — EP disclosed
WO-2024108216-A1 COMPOSITIONS COMPRISING OCTADECANEUROPEPTIDES (ODN) AND SYNTHETIC DERIVATIVES THEREOF AND METHODS OF USE FOR MODULATION OF FOOD INTAKE, OBESITY, BODY WEIGHT, NAUSEA, AND EMESIS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2024-05-23 — — WO disclosed