Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 20/20 | 1.00 |
| ▸ | PDCD1 | Q15116 | 19/20 | 1.00 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21290688 | 1.00 | CD274 (1.00) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL26318688 | 0.88 | CD274 (0.79) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL21290644 | 0.84 | PDCD1 (1.00) | CD274PDCD1 | |
| SCHEMBL21290731 | 0.81 | CD274 (1.00) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL21290640 | 0.78 | CD274 (1.00) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL26318795 | 0.76 | PDCD1 (0.83) | CD274PDCD1 | |
| SCHEMBL26331505 | 0.75 | CD274 (1.00) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL21290645 | 0.75 | CD274 (1.00) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL21290795 | 0.75 | CD274 (1.00) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL21291130 | 0.74 | CD274 (1.00) | CD274PDCD1PDCD1LG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084940-A | PD-1/PD-L1 inhibitors | 吉利德科学公司 | 2024-05-28 | — | — | CN | disclosed |