SCHEMBL30901573

SCHEMBL30901573

C=CCC1=C(CC=C)C2CCC1C(C(=O)O)C2C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.38
POLB P06746 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TSHR P16473 2/20 0.32
APEX1 P27695 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
GMNN O75496 1/20 0.31
LMNA P02545 1/20 0.31
PMP22 Q01453 1/20 0.31
TFPI2 P48307 1/20 0.31
TP53 P04637 1/20 0.31
NFKB1 P19838 1/20 0.31
THPO P40225 1/20 0.31
CYP2C19 P33261 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30901518 0.92 KDM4E (0.44) KDM4EPOLBL3MBTL1
SCHEMBL30901556 0.88 KDM4E (0.34) KDM4EPOLBL3MBTL1LMNA
SCHEMBL30901544 0.77 ABCC4 (0.39) KDM4EPOLBL3MBTL1LMNATAAR1
SCHEMBL31276570 0.72 POLB (0.42) KDM4EPOLBL3MBTL1TSHRAPEX1
SCHEMBL30901574 0.67 ABCC4 (0.36) KDM4EPOLBL3MBTL1
SCHEMBL30901587 0.67 GAA (0.34) KMT2A
SCHEMBL1325810 0.66 POLB (0.48) KDM4EPOLBL3MBTL1TSHRAPEX1
SCHEMBL30901535 0.65 POLB (0.36) KDM4EPOLBL3MBTL1TSHRTAAR1
SCHEMBL30901536 0.64 SCD (0.43) TSHRTDP1KMT2A
SCHEMBL31275667 0.64 POLB (0.52) KDM4EPOLBL3MBTL1TSHRAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118108878-A Organic polymer carrier and preparation method and application thereof 中国石油天然气股份有限公司 2024-05-31 CN claimed
CN-118108888-A Organic polymer carrier, Z-N catalyst, and preparation method and application thereof 中国石油天然气股份有限公司 2024-05-31 CN claimed
CN-118108888-A Organic polymer carrier, Z-N catalyst, and preparation method and application thereof 中国石油天然气股份有限公司 2024-05-31 CN disclosed