SCHEMBL30901792

SCHEMBL30901792

NC(=O)c1cccnc1N

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 2/20 0.70
PARP1 P09874 1/20 0.58
PRKCI P41743 2/20 0.56
MKNK1 Q9BUB5 1/20 0.53
MKNK2 Q9HBH9 1/20 0.53
KDM4E B2RXH2 5/20 0.49
ALDH1A1 P00352 3/20 0.49
HPGD P15428 2/20 0.49
HSD17B10 Q99714 2/20 0.49
MAPT P10636 4/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
RAB9A P51151 2/20 0.47
NPC1 O15118 1/20 0.47
AHR P35869 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
HTT P42858 1/20 0.46
TSHR P16473 2/20 0.45
CYP3A4 P08684 1/20 0.45
ALOX15 P16050 1/20 0.45
BLM P54132 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL310265 1.00 NAPRT (0.70) NAPRTPARP1PRKCIMKNK1MKNK2
Hydrochloric Acid SCHEMBL11788163 0.98 NAPRT (0.68) NAPRTPARP1PRKCIMKNK1MKNK2
2-Aminopyridine SCHEMBL15270616 0.89 NAPRT (0.58) NAPRTPARP1PRKCIMKNK1MKNK2
Propionic Acid SCHEMBL27888844 0.88 NAPRT (0.61) NAPRTPARP1PRKCIMKNK1MKNK2
Carbamic Acid SCHEMBL27881895 0.85 NAPRT (0.96) NAPRTPARP1PRKCIMKNK1MKNK2
SCHEMBL8198020 0.84 NAPRT (0.73) NAPRTPARP1PRKCIMKNK1MKNK2
SCHEMBL28253352 0.83 MKNK1 (0.58) NAPRTPARP1PRKCIMKNK1MKNK2
SCHEMBL31230208 0.83 MKNK1 (0.58) NAPRTPARP1PRKCIMKNK1MKNK2
SCHEMBL11098869 0.83 NAPRT (0.70) NAPRTPARP1PRKCIMKNK1MKNK2
SCHEMBL29530139 0.83 NAPRT (1.00) NAPRTPRKCIKDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117825598-A Method for detecting related substances in intermediate of toluene sodium sulfonate nicotinamide hydrazone polyethylene glycol bicyclo RGD peptide synthesis 北京吉伦泰科技有限公司 2024-04-05 CN disclosed