Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 3/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 10/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31029781 | 1.00 | KIT (0.53) | KITACHEBACE1MAP4K4PDGFRB | |
| SCHEMBL16637110 | 0.88 | KIT (0.52) | KITACHEBACE1MAP4K4PDGFRB | |
| SCHEMBL30902163 | 0.88 | KIT (0.52) | KITACHEBACE1MAP4K4PDGFRB | |
| SCHEMBL25656100 | 0.87 | KIT (0.53) | KITACHEBACE1MAP4K4PDGFRB | |
| SCHEMBL17030847 | 0.87 | KIT (0.53) | KITACHEBACE1MAP4K4PDGFRB | |
| SCHEMBL30826942 | 0.86 | KIT (0.51) | KITACHEBACE1MAP4K4PDGFRB | |
| SCHEMBL22029153 | 0.86 | KIT (0.51) | KITACHEBACE1MAP4K4PDGFRB | |
| SCHEMBL16637964 | 0.86 | KIT (0.52) | KITACHEBACE1MAP4K4PDGFRB | |
| SCHEMBL22028940 | 0.86 | KIT (0.52) | KITACHEBACE1MAP4K4PDGFRB | |
| SCHEMBL29611800 | 0.86 | KIT (0.52) | KITACHEBACE1MAP4K4PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117957219-A | Pyridine derivative and application thereof | 四川汇宇制药股份有限公司 | 2024-04-30 | — | — | CN | disclosed |