Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 4/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GALR2 | O43603 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31029660 | 1.00 | KIT (0.52) | KITMAP4K4LMNAMAPTHTT | |
| SCHEMBL31029680 | 0.88 | KIT (0.51) | KITMAP4K4LMNAMAPTHTT | |
| SCHEMBL18956123 | 0.87 | KIT (0.52) | KITMAP4K4LMNAMAPTHTT | |
| SCHEMBL16647196 | 0.86 | KIT (0.52) | KITMAP4K4LMNAMAPTHTT | |
| SCHEMBL21415508 | 0.83 | KIT (0.52) | KITMAP4K4LMNAMAPTHTT | |
| SCHEMBL16636962 | 0.82 | KIT (0.50) | KITMAP4K4LMNAMAPTHTT | |
| SCHEMBL26967337 | 0.82 | KIT (0.50) | KITMAP4K4LMNAMAPTHTT | |
| SCHEMBL29611722 | 0.82 | KIT (0.50) | KITMAP4K4LMNAMAPTHTT | |
| SCHEMBL26967418 | 0.82 | KIT (0.48) | KITMAP4K4GPR119GRIA1CNR1 | |
| SCHEMBL24918229 | 0.82 | KIT (0.49) | KITMAP4K4LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117957219-A | Pyridine derivative and application thereof | 四川汇宇制药股份有限公司 | 2024-04-30 | — | — | CN | disclosed |