Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2560233 | 0.92 | PTGS1 (0.49) | PTGS1PTGS2FAAHCASP1FNTA | |
| SCHEMBL12285559 | 0.92 | PTGS1 (0.49) | PTGS1PTGS2FAAHCASP1FNTA | |
| SCHEMBL18774100 | 0.92 | PTGS1 (0.49) | PTGS1PTGS2FAAHCASP1FNTA | |
| SCHEMBL2561561 | 0.92 | PTGS1 (0.49) | PTGS1PTGS2FAAHCASP1FNTA | |
| SCHEMBL2560238 | 0.92 | PTGS1 (0.49) | PTGS1PTGS2FAAHCASP1FNTA | |
| SCHEMBL31171013 | 0.89 | PTGS1 (0.38) | PTGS1PTGS2FAAHCASP1REN | |
| SCHEMBL31170999 | 0.89 | PTGS1 (0.38) | PTGS1PTGS2FAAHCASP1REN | |
| SCHEMBL30902880 | 0.85 | GLP1R (0.47) | PTGS1PTGS2HTTSMN1; SMN2HPGD | |
| SCHEMBL22644039 | 0.85 | NPY5R (0.43) | CASP1 | |
| SCHEMBL22267879 | 0.83 | PTGS1 (0.46) | PTGS1PTGS2FAAHCASP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105205-A1 | ANTIBODY-DRUG CONJUGATES (A2DCS) WITH ENZYMATICALLY CLEAVABLE GROUPS | BAYER AKTIENGESELLSCHAFT (DE) | 2024-05-23 | — | — | WO | disclosed |