SCHEMBL30903006

SCHEMBL30903006

Cn1cnnc1C1(c2cccc(-n3cc(Cl)c4c(Cl)c(CO)n(COCC[Si](C)(C)C)c4c3=O)c2)CC2(CC2)C1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 5/20 0.36
▸ CBL P22681 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30902999 0.93 CBLB (0.36) CBLBCBL
SCHEMBL30902995 0.93 CBLB (0.36) CBLBCBL
SCHEMBL30903018 0.92 CBLB (0.35) CBLBCBL
SCHEMBL30903049 0.90 CBLB (0.34) CBLBCBL
SCHEMBL30903001 0.88 CBLB (0.38) CBLBCBL
SCHEMBL30903024 0.88 CBLB (0.34) CBLBCBL
SCHEMBL30903014 0.86 CBLB (0.35) CBLBCBL
SCHEMBL30902987 0.82 CBLB (0.38) CBLBCBL
SCHEMBL30902976 0.82 CBLB (0.35) CBLBCBL
SCHEMBL30902990 0.82 CBLB (0.36) CBLBCBL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024105563-A1 SUBSTITUTED BICYCLIC PYRIDONE DERIVATIVES PFIZER INC. (US) 2024-05-23 — — WO disclosed
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