SCHEMBL30904843

CSCC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](C)N)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCC(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	NPY4R	P50391	9/20	0.58

▸	NPY5R	Q15761	8/20	0.58

▸	NPY1R	P25929	7/20	0.58

▸	IL23R	Q5VWK5	2/20	0.56

▸	NPY2R	P49146	5/20	0.54

▸	TFPI	P10646	1/20	0.53

▸	GLP1R	P43220	1/20	0.53

▸	GCGR	P47871	1/20	0.53

▸	GIPR	P48546	1/20	0.53

▸	RAMP3	O60896	1/20	0.51

▸	CALCR	P30988	1/20	0.51

▸	CCKBR	P32239	4/20	0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30904848	0.98	NPY4R (0.56)	NPY4RNPY5RNPY1RIL23RNPY2R
SCHEMBL30904844	0.97	NPY4R (0.60)	NPY4RNPY5RNPY1RIL23RNPY2R
SCHEMBL30904845	0.96	NPY4R (0.58)	NPY4RNPY5RNPY1RIL23RNPY2R
SCHEMBL30904847	0.95	NPY4R (0.58)	NPY4RNPY5RNPY1RIL23RNPY2R
SCHEMBL30904846	0.95	NPY4R (0.58)	NPY4RNPY5RNPY1RIL23RNPY2R
SCHEMBL30904842	0.94	NPY4R (0.56)	NPY4RNPY5RNPY1RIL23RNPY2R
SCHEMBL30904849	0.94	NPY4R (0.56)	NPY4RNPY5RNPY1RIL23RNPY2R
SCHEMBL30512654	0.88	NPY4R (0.62)	NPY4RNPY5RNPY1RNPY2RTFPI
SCHEMBL30524359	0.88	TFPI (0.61)	NPY4RNPY5RNPY1RIL23RTFPI
SCHEMBL30343592	0.87	NPY4R (0.54)	NPY4RNPY5RNPY1RIL23RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-117843726-A	Immunosuppression polypeptide, preparation method thereof and application thereof in preparation of medicine for treating rheumatoid arthritis	河北科技大学	2024-04-09	—	—	CN	disclosed