Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NNMT | P40261 | 1/20 | 0.39 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27403269 | 1.00 | KDM4E (0.40) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL30905517 | 0.90 | KDM4E (0.41) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL27403268 | 0.90 | KDM4E (0.41) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL27397994 | 0.84 | PKMYT1 (0.53) | KDM4EPKMYT1CDK1SRCLCK | |
| SCHEMBL30905518 | 0.84 | PKMYT1 (0.53) | KDM4EPKMYT1CDK1SRCLCK | |
| SCHEMBL27402503 | 0.84 | PARP1 (0.42) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL27402928 | 0.84 | PARP1 (0.39) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL27403348 | 0.84 | PKMYT1 (0.41) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL30905603 | 0.84 | PKMYT1 (0.41) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL27400650 | 0.81 | PARP1 (0.43) | KDM4ENNMTPKMYT1CDK1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4622967-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-01 | — | — | EP | disclosed |
| WO-2024112853-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |