Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 11/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 2/20 | 0.45 |
| ▸ | JAK3 | P52333 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27093010 | 1.00 | PDE4B (0.67) | PDE4BPOLBGAAMAPTDYRK1A | |
| SCHEMBL30906008 | 0.84 | PDE4B (0.47) | PDE4BATM | |
| SCHEMBL27092996 | 0.84 | PDE4B (0.47) | PDE4BATM | |
| SCHEMBL27002895 | 0.82 | PDE4B (0.58) | PDE4BDYRK1A | |
| SCHEMBL2773376 | 0.80 | PDE4B (1.00) | PDE4BPOLBJAK1JAK3 | |
| SCHEMBL20299423 | 0.80 | PDE4B (0.58) | PDE4BPOLBMAPTDYRK1A | |
| SCHEMBL29501995 | 0.80 | PDE4B (0.58) | PDE4BPOLBMAPTDYRK1A | |
| SCHEMBL1693608 | 0.80 | PDE4B (0.58) | PDE4BPOLBMAPTDYRK1A | |
| SCHEMBL15413264 | 0.78 | KDM4E (0.45) | POLBGAAMAPT | |
| SCHEMBL4332428 | 0.78 | PDE4B (1.00) | PDE4BGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117940426-A | DNA-dependent protein kinase inhibitors, compositions and uses thereof | 英特利亚治疗股份有限公司 | 2024-04-26 | — | — | CN | disclosed |