Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.50 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30906296 | 1.00 | CRBN (0.50) | CRBNDDB1USP30BRD4SCN9A | |
| SCHEMBL29265369 | 1.00 | CRBN (0.50) | CRBNDDB1USP30BRD4SCN9A | |
| SCHEMBL30738784 | 0.91 | CRBN (0.56) | CRBNDDB1USP30 | |
| SCHEMBL21933426 | 0.91 | CRBN (0.56) | CRBNDDB1USP30 | |
| SCHEMBL23572687 | 0.90 | CRBN (0.49) | CRBNDDB1USP30BRD4 | |
| SCHEMBL30159844 | 0.90 | CRBN (0.49) | CRBNDDB1USP30BRD4 | |
| SCHEMBL31682899 | 0.90 | CRBN (0.49) | CRBNDDB1USP30BRD4 | |
| SCHEMBL25631526 | 0.88 | CRBN (0.51) | CRBNDDB1USP30 | |
| SCHEMBL31134689 | 0.88 | CRBN (0.53) | CRBNDDB1USP30 | |
| SCHEMBL23572676 | 0.87 | CRBN (0.54) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598905-A2 | CEREBLON-RECRUITING BCL-XL/BCL-2 DUAL DEGRADERS | University of Florida Research Foundation, Incorporated (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024077023-A2 | CEREBLON-RECRUITING BCL-XL/BCL-2 DUAL DEGRADERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-04-11 | — | — | WO | disclosed |