SCHEMBL30906451

CC[C@H](C)[C@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](N)CS)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)O)C(C)C

nearest known ligand 0.72

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	KEAP1	Q14145	1/20	0.72

▸	GLP1R	P43220	14/20	0.68

▸	GCGR	P47871	9/20	0.68

▸	GIPR	P48546	6/20	0.68

▸	CALCR	P30988	3/20	0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30906372	0.94	GLP1R (0.64)	KEAP1GLP1RGCGRCALCR
SCHEMBL30906434	0.93	GLP1R (0.67)	KEAP1GLP1RGCGRGIPRCALCR
SCHEMBL30906504	0.92	GLP1R (0.66)	GLP1RGCGRGIPRCALCR
SCHEMBL30331625	0.91	GLP1R (0.71)	KEAP1GLP1RGCGRGIPR
SCHEMBL30473783	0.91	GLP1R (0.77)	KEAP1GLP1RGCGRGIPRCALCR
SCHEMBL30473769	0.91	GLP1R (0.77)	KEAP1GLP1RGCGRGIPRCALCR
SCHEMBL30721653	0.91	CALCR (0.75)	KEAP1GLP1RGCGRGIPRCALCR
SCHEMBL30721580	0.91	CALCR (0.75)	KEAP1GLP1RGCGRGIPRCALCR
SCHEMBL30906412	0.91	GLP1R (0.65)	GLP1RGCGRGIPRCALCR
SCHEMBL30906401	0.91	GLP1R (0.65)	GLP1RGCGRGIPRCALCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4598964-A2	ANTI-IGE ANTIBODIES	Abwiz Bio, Inc. (US)	2025-08-13	—	—	EP	disclosed
US-20240182599-A1	ANTI-IGE ANTIBODIES	ABWIZ BIO, INC.	2024-06-06	—	—	US	disclosed
WO-2024076785-A2	ANTI-IGE ANTIBODIES	ABWIZ BIO, INC. (US)	2024-04-11	—	—	WO	disclosed