SCHEMBL30906453

CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CS)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)O)[C@@H](C)O

nearest known ligand 0.63

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	CALCR	P30988	4/20	0.61

▸	EP300	Q09472	1/20	0.59

▸	HIF1A	Q16665	1/20	0.59

▸	MAPK8	P45983	1/20	0.58

▸	MAPK9	P45984	1/20	0.58

▸	MAPK10	P53779	1/20	0.58

▸	HCRTR1	O43613	1/20	0.58

▸	HCRTR2	O43614	1/20	0.58

▸	NPY2R	P49146	7/20	0.54

▸	NPY4R	P50391	7/20	0.54

▸	NPY5R	Q15761	7/20	0.54

▸	NPY1R	P25929	5/20	0.54

▸	CRHR1	P34998	1/20	0.53

▸	CRHR2	Q13324	1/20	0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30648485	0.91	CALCR (0.66)	CALCREP300HIF1AMAPK8MAPK9
SCHEMBL31182878	0.90	CALCR (0.70)	CALCRHCRTR1HCRTR2NPY2RNPY4R
SCHEMBL30712880	0.89	CALCR (0.61)	CALCREP300HIF1AHCRTR1HCRTR2
SCHEMBL30432825	0.88	CALCR (0.67)	CALCRMAPK8MAPK9MAPK10HCRTR1
SCHEMBL30495733	0.88	EP300 (0.66)	CALCREP300HIF1ANPY2RNPY4R
SCHEMBL31000946	0.88	CALCR (0.64)	CALCREP300HIF1AHCRTR1HCRTR2
SCHEMBL30607280	0.88	CALCR (0.59)	CALCREP300HIF1ANPY2RNPY4R
SCHEMBL31000906	0.86	CALCR (0.59)	CALCREP300HIF1AMAPK8MAPK9
SCHEMBL31656508	0.86	CALCR (0.78)	CALCRHCRTR1HCRTR2NPY2RNPY4R
SCHEMBL29679610	0.86	CALCRL (0.58)	CALCREP300HIF1AMAPK8MAPK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4598964-A2	ANTI-IGE ANTIBODIES	Abwiz Bio, Inc. (US)	2025-08-13	—	—	EP	disclosed
US-20240182599-A1	ANTI-IGE ANTIBODIES	ABWIZ BIO, INC.	2024-06-06	—	—	US	disclosed
WO-2024076785-A2	ANTI-IGE ANTIBODIES	ABWIZ BIO, INC. (US)	2024-04-11	—	—	WO	disclosed