SCHEMBL30906571

CC(C)[C@H](NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CO)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O)C(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	MAPK8	P45983	1/20	0.59

▸	MAPK9	P45984	1/20	0.59

▸	MAPK10	P53779	1/20	0.59

▸	IL23R	Q5VWK5	1/20	0.58

▸	CALCR	P30988	5/20	0.58

▸	EPHA2	P29317	2/20	0.58

▸	NPY2R	P49146	7/20	0.58

▸	NPY4R	P50391	7/20	0.58

▸	NPY5R	Q15761	7/20	0.58

▸	NPY1R	P25929	5/20	0.58

▸	RAMP3	O60896	1/20	0.57

▸	EP300	Q09472	1/20	0.57

▸	HIF1A	Q16665	1/20	0.57

▸	TFPI	P10646	1/20	0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30906545	0.99	MAPK8 (0.60)	MAPK8MAPK9MAPK10IL23RCALCR
SCHEMBL30906496	0.98	MAPK8 (0.61)	MAPK8MAPK9MAPK10IL23RCALCR
SCHEMBL30906426	0.97	MAPK8 (0.60)	MAPK8MAPK9MAPK10IL23RCALCR
SCHEMBL30906549	0.96	NMUR2 (0.59)	MAPK8MAPK9MAPK10CALCREPHA2
SCHEMBL30906388	0.96	MAPK8 (0.61)	MAPK8MAPK9MAPK10CALCREPHA2
SCHEMBL30906437	0.95	EPHA2 (0.61)	MAPK8MAPK9MAPK10IL23RCALCR
SCHEMBL30906416	0.94	EPHA2 (0.59)	MAPK8MAPK9MAPK10CALCREPHA2
SCHEMBL30906542	0.93	EPHA2 (0.64)	MAPK8MAPK9MAPK10CALCREPHA2
SCHEMBL30906523	0.92	MAPK8 (0.62)	MAPK8MAPK9MAPK10CALCREPHA2
SCHEMBL30906430	0.91	EPHA2 (0.57)	MAPK8MAPK9MAPK10CALCREPHA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4598964-A2	ANTI-IGE ANTIBODIES	Abwiz Bio, Inc. (US)	2025-08-13	—	—	EP	disclosed
US-20240182599-A1	ANTI-IGE ANTIBODIES	ABWIZ BIO, INC.	2024-06-06	—	—	US	disclosed
WO-2024076785-A2	ANTI-IGE ANTIBODIES	ABWIZ BIO, INC. (US)	2024-04-11	—	—	WO	disclosed