Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 9/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | TAS2R8 | Q9NYW2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2936825 | 0.88 | IGF1R (0.52) | IGF1RHDAC1HDAC6TAS2R8 | |
| SCHEMBL2935351 | 0.83 | IGF1R (0.63) | IGF1RTAS2R8 | |
| SCHEMBL13177341 | 0.81 | IGF1R (0.49) | IGF1RHDAC1HDAC6TAS2R8 | |
| SCHEMBL2935325 | 0.77 | IGF1R (0.53) | IGF1RTAS2R8 | |
| SCHEMBL2941564 | 0.77 | IGF1R (0.53) | IGF1RTAS2R8 | |
| SCHEMBL13076385 | 0.76 | IGF1R (0.52) | IGF1RTAS2R8 | |
| SCHEMBL2939788 | 0.73 | IGF1R (0.48) | IGF1RTAS2R8 | |
| SCHEMBL2939756 | 0.72 | IGF1R (0.66) | IGF1RTAS2R8 | |
| SCHEMBL19410365 | 0.72 | IGF1R (0.49) | IGF1RHDAC1HDAC6TAS2R8 | |
| SCHEMBL13177530 | 0.71 | IGF1R (0.50) | IGF1RHDAC1HDAC6TAS2R8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-B1 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA SA (FR) | 2010-09-22 | — | — | EP | disclosed |