Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 11/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 9/20 | 0.49 |
| ▸ | CDK4 | P11802 | 7/20 | 0.49 |
| ▸ | CCND1 | P24385 | 7/20 | 0.49 |
| ▸ | CCND3 | P30281 | 7/20 | 0.49 |
| ▸ | CDK6 | Q00534 | 7/20 | 0.49 |
| ▸ | CDK1 | P06493 | 7/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 7/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.49 |
| ▸ | CDK7 | P50613 | 3/20 | 0.49 |
| ▸ | CDK9 | P50750 | 3/20 | 0.49 |
| ▸ | CCNH | P51946 | 3/20 | 0.49 |
| ▸ | MNAT1 | P51948 | 3/20 | 0.49 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27213173 | 1.00 | CDK2 (0.49) | CDK2CCNE1CDK4CCND1CCND3 | |
| SCHEMBL30906796 | 0.93 | CDK2 (0.49) | CDK2CCNE1CDK4CCND1CCND3 | |
| SCHEMBL27213196 | 0.93 | CDK2 (0.49) | CDK2CCNE1CDK4CCND1CCND3 | |
| SCHEMBL27213243 | 0.93 | CDK2 (0.49) | CDK2CCNE1CDK4CCND1CCND3 | |
| SCHEMBL30906805 | 0.93 | CDK2 (0.49) | CDK2CCNE1CDK4CCND1CCND3 | |
| SCHEMBL27213227 | 0.90 | CDK2 (0.38) | CDK2CCNE1CDK4CCND1CCND3 | |
| SCHEMBL30906832 | 0.90 | CDK2 (0.38) | CDK2CCNE1CDK4CCND1CCND3 | |
| SCHEMBL30906873 | 0.88 | CDK2 (0.49) | CDK2CCNE1CDK4CCND1CCND3 | |
| SCHEMBL27213200 | 0.88 | CDK2 (0.49) | CDK2CCNE1CDK4CCND1CCND3 | |
| SCHEMBL30906831 | 0.88 | CCND3 (0.47) | CDK2CCNE1CDK4CCND1CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024077216-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | PRELUDE THERAPEUTICS INCORPORATED (US) | 2024-04-11 | — | — | WO | claimed |
| WO-2024077216-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | PRELUDE THERAPEUTICS INCORPORATED (US) | 2024-04-11 | — | — | WO | disclosed |