Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 15/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 14/20 | 0.50 |
| ▸ | CDK4 | P11802 | 9/20 | 0.50 |
| ▸ | CCND1 | P24385 | 9/20 | 0.50 |
| ▸ | CCND3 | P30281 | 9/20 | 0.50 |
| ▸ | CDK6 | Q00534 | 9/20 | 0.50 |
| ▸ | CDK1 | P06493 | 9/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 9/20 | 0.50 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.50 |
| ▸ | CDK7 | P50613 | 4/20 | 0.50 |
| ▸ | CDK9 | P50750 | 4/20 | 0.50 |
| ▸ | CCNH | P51946 | 4/20 | 0.50 |
| ▸ | MNAT1 | P51948 | 4/20 | 0.50 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | CCNK | O75909 | 2/20 | 0.35 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27213124 | 1.00 | CDK2 (0.50) | CDK2CCNE1CDK4CCND1CCND3 | |
| SCHEMBL30906872 | 0.93 | CCNE1 (0.50) | CDK2CCNE1CDK4CCND1CCND3 | |
| SCHEMBL30906879 | 0.93 | CCNE1 (0.50) | CDK2CCNE1CDK4CCND1CCND3 | |
| SCHEMBL27213108 | 0.93 | CCNE1 (0.50) | CDK2CCNE1CDK4CCND1CCND3 | |
| SCHEMBL27213239 | 0.93 | CCNE1 (0.50) | CDK2CCNE1CDK4CCND1CCND3 | |
| SCHEMBL27213258 | 0.90 | CCNE1 (0.44) | CDK2CCNE1CDK4CCND1CCND3 | |
| SCHEMBL30906850 | 0.90 | CCNE1 (0.44) | CDK2CCNE1CDK4CCND1CCND3 | |
| SCHEMBL27213140 | 0.89 | CDK2 (0.61) | CDK2CCNE1CDK4CCND1CCND3 | |
| SCHEMBL30906860 | 0.89 | CDK2 (0.61) | CDK2CCNE1CDK4CCND1CCND3 | |
| SCHEMBL30906884 | 0.88 | CDK6 (0.47) | CDK2CCNE1CDK4CCND1CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024077216-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | PRELUDE THERAPEUTICS INCORPORATED (US) | 2024-04-11 | — | — | WO | claimed |
| WO-2024077216-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | PRELUDE THERAPEUTICS INCORPORATED (US) | 2024-04-11 | — | — | WO | disclosed |