Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 17/20 | 0.47 |
| ▸ | CCND1 | P24385 | 16/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 14/20 | 0.47 |
| ▸ | CDK2 | P24941 | 14/20 | 0.47 |
| ▸ | CCND3 | P30281 | 6/20 | 0.43 |
| ▸ | CDK4 | P11802 | 5/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27213197 | 1.00 | CDK6 (0.47) | CDK6CCND1CCNE1CDK2CCND3 | |
| SCHEMBL27213207 | 0.91 | CCND1 (0.51) | CDK6CCND1CCNE1CDK2CCND3 | |
| SCHEMBL27213177 | 0.90 | CCNE1 (0.49) | CDK6CCND1CCNE1CDK2CCND3 | |
| SCHEMBL27213220 | 0.90 | CDK6 (0.46) | CDK6CCND1CCNE1CDK2CCND3 | |
| SCHEMBL27213272 | 0.90 | CCNE1 (0.49) | CDK6CCND1CCNE1CDK2CCND3 | |
| SCHEMBL30906768 | 0.89 | CDK6 (0.45) | CDK6CCND1CCNE1CDK2CCND3 | |
| SCHEMBL27213148 | 0.89 | CDK6 (0.45) | CDK6CCND1CCNE1CDK2CCND3 | |
| SCHEMBL30906843 | 0.82 | CCNE1 (0.49) | CDK6CCND1CCNE1CDK2CCND3 | |
| SCHEMBL27213251 | 0.82 | CCNE1 (0.49) | CDK6CCND1CCNE1CDK2CCND3 | |
| SCHEMBL30906852 | 0.79 | CCNE1 (0.52) | CDK6CCND1CCNE1CDK2CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024077216-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | PRELUDE THERAPEUTICS INCORPORATED (US) | 2024-04-11 | — | — | WO | claimed |
| WO-2024077216-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | PRELUDE THERAPEUTICS INCORPORATED (US) | 2024-04-11 | — | — | WO | disclosed |