Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 17/20 | 0.51 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.43 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30907190 | 0.82 | ABL1 (0.49) | ABL1MAP4K1KITPDGFRA | |
| SCHEMBL30907625 | 0.81 | ABL1 (0.56) | ABL1MAP4K1KITPDGFRA | |
| SCHEMBL30907204 | 0.79 | ABL1 (0.60) | ABL1 | |
| SCHEMBL30907310 | 0.79 | ABL1 (0.60) | ABL1 | |
| SCHEMBL30907276 | 0.79 | ABL1 (0.60) | ABL1 | |
| SCHEMBL30907153 | 0.78 | ABL1 (0.52) | ABL1MAP4K1 | |
| SCHEMBL30907435 | 0.77 | ABL1 (0.51) | ABL1MAP4K1KITPDGFRA | |
| SCHEMBL30907211 | 0.77 | ABL1 (0.62) | ABL1 | |
| SCHEMBL30907214 | 0.77 | ABL1 (0.62) | ABL1 | |
| SCHEMBL30907230 | 0.77 | ABL1 (0.62) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097953-A1 | NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2024-05-10 | — | — | WO | disclosed |