Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 9/20 | 0.46 |
| ▸ | MAP4K1 | Q92918 | 4/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30907569 | 0.88 | ABL1 (0.44) | ABL1MAP4K1CRBN | |
| SCHEMBL30907521 | 0.83 | ABL1 (0.39) | ABL1MAP4K1 | |
| SCHEMBL30907358 | 0.81 | ABL1 (0.43) | ABL1MAP4K1 | |
| SCHEMBL30907246 | 0.81 | ABL1 (0.43) | ABL1MAP4K1 | |
| SCHEMBL30907415 | 0.81 | ABL1 (0.43) | ABL1MAP4K1 | |
| SCHEMBL30907111 | 0.80 | ABL1 (0.43) | ABL1CRBN | |
| SCHEMBL30907187 | 0.80 | ABL1 (0.59) | ABL1MAP4K1 | |
| SCHEMBL30907127 | 0.79 | ABL1 (0.48) | ABL1MAP4K1CRBN | |
| SCHEMBL30907457 | 0.76 | ABL1 (0.61) | ABL1MAP4K1 | |
| SCHEMBL24666788 | 0.76 | SRC (0.39) | ABL1CRBNJAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097953-A1 | NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2024-05-10 | — | — | WO | disclosed |