Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 11/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | MAP4K1 | Q92918 | 7/20 | 0.36 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30907334 | 0.92 | ABL1 (0.46) | ABL1GSK3BDYRK1AMAP4K1 | |
| SCHEMBL30907569 | 0.86 | ABL1 (0.44) | ABL1MAP4K1 | |
| SCHEMBL30907475 | 0.84 | GSK3B (0.41) | ABL1GSK3BDYRK1AMAP4K1SREBF2 | |
| SCHEMBL30907457 | 0.82 | ABL1 (0.61) | ABL1MAP4K1 | |
| SCHEMBL30907666 | 0.82 | ABL1 (0.50) | ABL1GSK3BDYRK1A | |
| SCHEMBL30907374 | 0.82 | ABL1 (0.43) | ABL1MAP4K1 | |
| SCHEMBL30907169 | 0.82 | ABL1 (0.43) | ABL1MAP4K1 | |
| SCHEMBL30907548 | 0.80 | ABL1 (0.54) | ABL1GSK3BDYRK1A | |
| SCHEMBL30907177 | 0.80 | ABL1 (0.33) | ABL1 | |
| SCHEMBL30907294 | 0.80 | ABL1 (0.57) | ABL1GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097953-A1 | NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2024-05-10 | — | — | WO | disclosed |