SCHEMBL30908402

SCHEMBL30908402

CCOC(=O)c1cnc(N2CCOCC2)s1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OGA O60502 2/20 0.55
PIK3CA P42336 2/20 0.54
MAPK1 P28482 2/20 0.49
ALDH1A1 P00352 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
CDC7 O00311 1/20 0.47
DBF4 Q9UBU7 1/20 0.47
TP53 P04637 2/20 0.47
USP2 O75604 1/20 0.47
RECQL P46063 1/20 0.47
HSD17B10 Q99714 1/20 0.47
KDM4E B2RXH2 2/20 0.47
RXFP1 Q9HBX9 1/20 0.46
ALOX15 P16050 1/20 0.45
PKM P14618 1/20 0.45
PARP1 P09874 1/20 0.44
TNK2 Q07912 1/20 0.44
TNK1 Q13470 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16982078 0.85 OGA (0.59) OGAALDH1A1CDC7DBF4PARP1
SCHEMBL5334339 0.84 OGA (0.55) OGAALDH1A1CDC7DBF4PARP1
SCHEMBL3787851 0.83 OGA (0.57) OGACDC7DBF4RXFP1PARP1
Hydrochloric Acid SCHEMBL17541458 0.83 OGA (0.54) OGACDC7DBF4PARP1TNK2
SCHEMBL31281641 0.81 HRH3 (0.53) OGACDC7DBF4PARP1TNK2
SCHEMBL8217601 0.80 HDAC3 (0.52) OGAPIK3CAMAPK1ALDH1A1KDM4E
SCHEMBL17452611 0.80 OGA (0.50) OGAPIK3CAKDM4EHDAC3HDAC4
SCHEMBL2822653 0.79 OGA (0.50) OGAMAPK1ALDH1A1CDC7DBF4
SCHEMBL3097936 0.79 POLB (0.51) OGAPIK3CAALDH1A1HSD17B10KDM4E
SCHEMBL3155607 0.78 OGA (0.52) OGARXFP1PARP1TNK2TNK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024074611-A1 PRMT5 INHIBITORS Ryvu Therapeutics S.A. (PL) 2024-04-11 WO disclosed