Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 1/20 | 0.48 |
| ▸ | CDC7 | O00311 | 1/20 | 0.47 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.37 |
| ▸ | OGA | O60502 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23159723 | 0.90 | HCRTR2 (0.55) | HCRTR2CDC7DBF4MAPK1HSD17B10 | |
| SCHEMBL15889436 | 0.88 | HCRTR2 (0.51) | HCRTR2CDC7DBF4MAPK1HSD17B10 | |
| SCHEMBL15896608 | 0.86 | HCRTR2 (0.50) | HCRTR2CDC7DBF4MAPK1HSD17B10 | |
| SCHEMBL31704833 | 0.85 | LRRK2 (0.40) | HCRTR2HSD17B10HPGD | |
| SCHEMBL15376175 | 0.84 | HCRTR2 (0.48) | HCRTR2CDC7DBF4HSD17B10TP53 | |
| SCHEMBL31705326 | 0.84 | HCRTR2 (0.48) | HCRTR2CDC7DBF4HSD17B10TP53 | |
| SCHEMBL31705910 | 0.81 | HCRTR2 (0.48) | HCRTR2CDC7DBF4HSD17B10OGA | |
| SCHEMBL21381077 | 0.81 | HCRTR2 (0.48) | HCRTR2CDC7DBF4MAPK1HSD17B10 | |
| SCHEMBL15376745 | 0.80 | HCRTR2 (0.55) | HCRTR2CDC7DBF4HPGDHTT | |
| SCHEMBL23512729 | 0.80 | HCRTR2 (0.47) | HCRTR2CDC7DBF4HSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |