Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.74 |
| ▸ | DRD2 | P14416 | 7/20 | 0.73 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.69 |
| ▸ | HTR1A | P08908 | 4/20 | 0.64 |
| ▸ | HTR2A | P28223 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.64 |
| ▸ | HTR6 | P50406 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30909227 | 0.99 | KDM4E (0.76) | KDM4ELMNAALOX15DRD2SIGMAR1 | |
| SCHEMBL11325290 | 0.99 | KDM4E (0.76) | KDM4ELMNAALOX15DRD2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL11315781 | 0.99 | KDM4E (0.76) | KDM4ELMNAALOX15DRD2SIGMAR1 | |
| Hydrogen Sulfide SCHEMBL27496556 | 0.94 | KDM4E (0.76) | KDM4ELMNAALOX15DRD2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL11313113 | 0.90 | KDM4E (0.81) | KDM4ELMNAALOX15DRD2SIGMAR1 | |
| SCHEMBL11315106 | 0.90 | KDM4E (0.81) | KDM4ELMNAALOX15DRD2SIGMAR1 | |
| SCHEMBL14640613 | 0.86 | KDM4E (0.67) | KDM4ELMNAALOX15DRD2SIGMAR1 | |
| SCHEMBL4491839 | 0.86 | KDM4E (0.70) | KDM4ELMNAALOX15DRD2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL11325899 | 0.85 | KDM4E (1.00) | KDM4ELMNAALOX15DRD2SIGMAR1 | |
| SCHEMBL11321052 | 0.85 | KDM4E (1.00) | KDM4ELMNAALOX15DRD2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |