Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 16/20 | 0.51 |
| ▸ | HTR1B | P28222 | 14/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | HTR1F | P30939 | 2/20 | 0.49 |
| ▸ | CCR2 | P41597 | 4/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7484592 | 1.00 | HTR1D (0.51) | HTR1DHTR1BHTR1AHTR1FCCR2 | |
| SCHEMBL7486041 | 0.88 | HTR1D (0.50) | HTR1DHTR1BHTR1AHTR1FCCR2 | |
| SCHEMBL7481470 | 0.86 | HTR1D (0.52) | HTR1DHTR1BHTR1AHTR1FCCR2 | |
| SCHEMBL30908878 | 0.84 | HTR1D (0.47) | HTR1DHTR1BHTR1AHTR1FCHRM2 | |
| SCHEMBL8385340 | 0.84 | HTR1D (0.47) | HTR1DHTR1BHTR1AHTR1FCHRM2 | |
| SCHEMBL7480395 | 0.83 | HTR1D (0.62) | HTR1DHTR1BHTR1AHTR1FCHRM2 | |
| SCHEMBL8721021 | 0.80 | HTR1D (0.47) | HTR1DHTR1BHTR1AHTR1FCHRM2 | |
| SCHEMBL7490112 | 0.80 | HTR1D (0.52) | HTR1DHTR1BHTR1AHTR1FCCR2 | |
| SCHEMBL7489436 | 0.80 | HTR1D (0.60) | HTR1DHTR1BHTR1AHTR1FCHRM2 | |
| SCHEMBL30908885 | 0.79 | HTR1D (0.56) | HTR1DHTR1BHTR1AHTR1FCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |