Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 20/20 | 0.56 |
| ▸ | HTR1B | P28222 | 17/20 | 0.56 |
| ▸ | HTR1A | P08908 | 3/20 | 0.56 |
| ▸ | HTR1F | P30939 | 3/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7485124 | 1.00 | HTR1D (0.56) | HTR1DHTR1BHTR1AHTR1FCHRM2 | |
| SCHEMBL7484950 | 0.92 | HTR1D (0.55) | HTR1DHTR1BHTR1AHTR1FCHRM2 | |
| SCHEMBL7488488 | 0.90 | HTR1D (0.58) | HTR1DHTR1BHTR1AHTR1FCHRM2 | |
| SCHEMBL7479141 | 0.89 | HTR1D (0.54) | HTR1DHTR1BHTR1AHTR1FCHRM2 | |
| SCHEMBL7479333 | 0.88 | HTR1D (0.62) | HTR1DHTR1BHTR1AHTR1FCHRM2 | |
| SCHEMBL7480395 | 0.87 | HTR1D (0.62) | HTR1DHTR1BHTR1AHTR1FCHRM2 | |
| SCHEMBL7479741 | 0.87 | HTR1D (0.72) | HTR1DHTR1BHTR1AHTR1FCHRM2 | |
| SCHEMBL7482257 | 0.87 | HTR1D (0.66) | HTR1DHTR1BHTR1AHTR1FCHRM2 | |
| SCHEMBL7484627 | 0.86 | HTR1D (0.60) | HTR1DHTR1BHTR1AHTR1FCHRM2 | |
| SCHEMBL7490650 | 0.86 | HTR1D (0.76) | HTR1DHTR1BHTR1AHTR1FCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |