Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4246484 | 0.78 | PARP1 (0.41) | PARP1GPR119HSD17B10 | |
| SCHEMBL2253695 | 0.76 | NR1H2 (0.44) | PARP1GPR119 | |
| SCHEMBL28312822 | 0.75 | PARP1 (0.46) | PARP1USP2SMN1; SMN2RECQLHSD17B10 | |
| SCHEMBL102293 | 0.75 | PARP1 (0.46) | PARP1USP2SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL102292 | 0.75 | PARP1 (0.46) | PARP1USP2SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL103217 | 0.75 | PARP1 (0.46) | PARP1USP2SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL16908312 | 0.74 | PARP1 (0.43) | PARP1GPR119HSD17B10HPGDCHRM2 | |
| SCHEMBL29282470 | 0.74 | PARP1 (0.43) | PARP1GPR119HSD17B10HPGDCHRM2 | |
| SCHEMBL19880895 | 0.74 | PARP1 (0.43) | PARP1GPR119HSD17B10HPGDCHRM2 | |
| SCHEMBL30945108 | 0.74 | NR1H2 (0.40) | PARP1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980297-A | Substituted aminopyridine compounds as EGFR inhibitors | 柳韩洋行 | 2024-05-03 | — | — | CN | disclosed |