Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PGK1 | P00558 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2180477 | 0.88 | CYP3A4 (0.67) | CYP3A4KDM4EMAPTALDH1A1CYP1A2 | |
| SCHEMBL28564819 | 0.83 | CYP3A4 (0.50) | CYP3A4KDM4EMAPTALDH1A1CYP1A2 | |
| SCHEMBL4280713 | 0.80 | KCNH2 (0.54) | CYP3A4KDM4EMAPTALDH1A1CYP1A2 | |
| SCHEMBL31544587 | 0.80 | KCNH2 (0.54) | CYP3A4KDM4EMAPTALDH1A1CYP1A2 | |
| SCHEMBL10442103 | 0.79 | FFAR1 (0.41) | CYP3A4KDM4EMAPTALDH1A1CYP1A2 | |
| SCHEMBL6297820 | 0.79 | KDM4E (0.57) | CYP3A4KDM4EMAPTALDH1A1CYP1A2 | |
| SCHEMBL10454531 | 0.79 | CYP3A4 (0.57) | CYP3A4KDM4EMAPTALDH1A1CYP1A2 | |
| SCHEMBL21114150 | 0.79 | CYP3A4 (0.57) | CYP3A4KDM4EMAPTALDH1A1CYP1A2 | |
| SCHEMBL15022608 | 0.79 | KDM4E (0.57) | CYP3A4KDM4EMAPTALDH1A1CYP1A2 | |
| SCHEMBL2410459 | 0.77 | MAPT (0.54) | CYP3A4KDM4EMAPTALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118125978-A | MYC inhibitor and preparation method and application thereof | 安徽中医药大学 | 2024-06-04 | — | — | CN | disclosed |