SCHEMBL309133

SCHEMBL309133

CCCCCCCCCCOc1cc[c]cc1

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.60
LTA4H P09960 4/20 0.53
TP53 P04637 2/20 0.53
TSHR P16473 2/20 0.53
PLA2G4B P0C869 3/20 0.51
RARB P10826 3/20 0.49
NPC1 O15118 1/20 0.49
LMNA P02545 1/20 0.49
GAA P10253 1/20 0.49
MAPT P10636 1/20 0.49
ALOX15 P16050 1/20 0.49
RAB9A P51151 1/20 0.49
HSD17B10 Q99714 1/20 0.49
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 2/20 0.46
HPGD P15428 2/20 0.46
HTT P42858 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
PLA2G4A P47712 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL659360 1.00 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL338316 1.00 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL1609987 1.00 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL1611001 1.00 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL987954 1.00 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL77477 1.00 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL9121701 1.00 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL263776 1.00 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL988767 1.00 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL1610778 1.00 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 756 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117964602-A Benzothiophene ketone derivative and preparation method and application thereof 广州医科大学 2024-05-03 CN claimed
CN-107442038-B Ultraviolet response amino acid surfactant and preparation method thereof 广州天赐高新材料股份有限公司 2019-08-09 CN claimed
CN-107442038-A Ultraviolet response amino acid surfactant and preparation method thereof 广州天赐高新材料股份有限公司 2017-12-08 CN claimed
US-7619055-B2 Linked arylamine polymers and electronic devices generated therefrom XEROX CORPORATION (US) 2009-11-17 US claimed
US-20080194859-A1 Polyurea Compositions and Compounds for the Preparation Thereof Sawyer, Kenneth I. (US) 2008-08-14 US claimed
EP-1282604-B1 SUBSTITUTED CAPROLACTAM CARBONATES AND ETHERS AND THEIR USE AS ANTI-TUMOR AGENTS NOVARTIS AG (CH) 2008-01-09 EP claimed
US-20070170398-A1 Polypropylene resin compositions SCHMIDT HANS-WERNER 2007-07-26 US claimed
EP-1751206-A2 POLYUREA COMPOSITIONS AND COMPOUNDS FOR THE PREPARATION THEREOF Sawyer, Kenneth I. (US) 2007-02-14 EP claimed
EP-1087946-B1 ARYL ALKANOYLPYRIDAZINES MERCK PATENT GMBH (DE) 2007-01-10 EP claimed
EP-1366116-B1 POLYPROPYLENE RESIN COMPOSITIONS CIBA SC HOLDING AG (CH) 2006-07-19 EP claimed
EP-1131297-A1 CERTAIN SUBSTITUTED CAPROLACTAMS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN TREATING TUMORS Novartis AG (CH) 2001-09-12 EP claimed
US-6239220-B1 Recovery of triarylmethyl halide protecting groups cleaved during oligonucleotide synthesis ISIS PHARMACEUTICALS, INC. 2001-05-29 US claimed
US-6239127-B1 CHEMOTHERAPY OF TUMORS, EXHIBIT A HIGH DEGREE OF SELECTIVITY IN KILLING CANCER CELLS. NOVARTIS AG (CH) 2001-05-29 US claimed
US-6124484-A Recovery of triarylmethyl halide protecting groups cleaved during oligonucleotide synthesis ISIS PHARMACEUTICALS, INC. (US) 2000-09-26 US claimed
EP-1005338-A1 SUBSTITUTED AURONE DERIVATIVES PHYTERA, INC. (US) 2000-06-07 EP claimed
WO-2000029382-A1 CERTAIN SUBSTITUTED CAPROLACTAMS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN TREATING TUMORS NOVARTIS AG (CH) 2000-05-25 WO claimed
WO-2000004062-A1 RECOVERY OF TRIARYLMETHYL HALIDE PROTECTING GROUPS CLEAVED DURING OLIGONUCLEOTIDE SYNTHESIS ISIS PHARMACEUTICALS, INC. (US) 2000-01-27 WO claimed
WO-1999004789-A1 SUBSTITUTED AURONE DERIVATIVES PHYTERA, INC. (US) 1999-02-04 WO claimed
EP-0267585-B1 FLUOROALKANE DERIVATIVE, ITS COMPOSITION AND LIQUID CRYSTAL DEVICE USING SAME CANON KABUSHIKI KAISHA (JP) 1993-09-15 EP claimed
US-4604471-A PLASTIC STABILIZERS BASF AKTIENGESELLSCHAFT (DE) 1986-08-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080194859-A1 Polyurea Compositions and Compounds for the Preparation Thereof PUF60, PCNA, PARG NR5A1 4801/4885LTA4H 4166/4885TP53 714/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.